I recently had the pleasure of working with Goldfinch to help characterize its high-throughput organoid platform, which it developed for preclinical validation of potential therapies for kidney disease.
Lots of folks in the life sciences are finding themselves suddenly thrown into an involuntary work-from-home situation. Here at Diamond Age we’ve been working remotely from our homes for some time, so we’d like to say “Welcome!” and offer a few hard-won tips to make the transition (hopefully) easier. A few of these are common… Read More »Working from Home
At Diamond Age Data Science, we make extensive use of RMarkdown and RStudio. These tools let us merge our analyses and reporting into a single framework and give our customers a way to inspect our methodology and reproduce our analyses on their own (if they wish). They also enable our customers to customize their views… Read More »Tutorial: Scientific reporting from Jupyterlab with R Markdown
We’ll be hosting the venerable Boston Computational Biology and Bioinformatics Meetup in Cambridge, at the Asgard, December 10th. Please come join us for food and drinks and much discussion of all things bioinformatics. This meetup is a fantastic place to meet folks who are in the field, whether they’re just starting out or long-time veterans.… Read More »Come visit us December 10th
One of the common analysis tasks we have at Diamond Age is to analyze single cell RNA-seq data. Our customers are largely therapeutics-development biotechs who use this new technology to assess the impact of their development candidates on gene expression in selected cell types. scRNA-seq is a very different beast than its apparent predecessor, bulk… Read More »The challenge of single-cell RNA-seq and differential expression
Here we are in that funny week at the end of the year, when the projects have mostly wrapped up and we take a breather and look at both the year behind and the year ahead. In short, 2018 has been an amazing, exciting year with a lot of work and a lot of success.… Read More »2018 in Review
If you missed our presentation at the North Shore Technology Council’s First Friday event, you can check out the slides on SlideShare. We co-presented with Huseyin Mehmet of Zafgen, Inc. Huseyin talked about what we do for them, from cross-dataset analysis to technology recommendations to app development. I talked about what you should look for… Read More »Taking your bioinformatics to the next level
Want to learn more about computational biology in a therapeutics context? I’ll be co-presenting with Huseyin Mehmet of Zafgen next Friday, December 7th at the Woburn Trade Center. We’ll be talking about making effective use of computational biology data for drug discovery and development, and also describing how the collaboration between Diamond Age and Zafgen… Read More »We’re presenting!
It’s Thanksgiving Day, and I’d like to take a minute to say “Thank you” to the people who have made Diamond Age possible, starting with our customers. We’ll have a proper ‘Customers’ page up here soon enough, but in the meantime, thank you to Decibel Therapeutics, Voyager Therapeutics, 1CellBio, Aquinnah Pharmaceuticals, and Zafgen, Inc. As… Read More »Thanksgiving 2018
Source control is not just for software engineers. Using the tools that coders have written to support their work can make a computational biologist’s life massively easier. You’ll find that having a versioned, trackable backup of your analytic scripts is a lifesaver, over and over again. Backups. If you are checking code into a get… Read More »Three reasons to use Git for bioinformatics projects
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