Our current services include:
Advising and strategy
- Review of CRO analysis for correctness and completeness
- Review of poor or unexpected results to determine causes (e.g., was this a lab problem or an analysis problem?)
- Experimental design review — making sure your experiment is adequately powered to yield the answers you need
- Bioinformatics “concierge service” — comprehensive advising on experimental design, CRO selection, data analysis, software selection, etc.
- Guidance on software engineering, informatics, data management, and knowledge architecture
- Development of best practices for analyzing high-throughput data
- Total bioinformatics department replacement
Therapeutics-focused functions
- Biomarker development
- Mechanism of action evaluation: proteomics, transcriptomics, and pathway analysis
- Patient selection
- New indication nominations
Hands-on data analysis
- Statistical modeling and machine learning applications for therapeutics development
- Transcriptional profiling and pathway analysis
- Statistical genetics and comparative sequence analysis
- Single-cell RNA-seq: cell type ID, rare population detection, perturbation analysis, development/trajectory analysis
- Single dataset de novo analysis: proteomics, metabolomics, RNA-seq, ribosome profiling (Ribo-seq)
- Computational chemistry: new target assessments using computational chemistry approaches and structure-based drug design methods
Engineering and infrastructure
- Pipeline assessments and recommendations
- Dashboard and web application builds
- Custom analysis pipeline builds
- Production-grade hardening of first-draft analysis tools and systems
If you don’t see your needs represented here, let us know — we’re happy to develop custom solutions and services.