Eleanor Howe, founder and CEO
Eleanor has been working at the cutting edge of bioinformatics for over 15 years. As founder of Diamond Age, she led the company’s evolution from a small, project-based service provider to a full-fledged consultancy that works closely with clients to tackle their most difficult research challenges.
Before founding Diamond Age, Eleanor served as the sole bioinformatician in the Center for the Development of Therapeutics at the Broad Institute of MIT and Harvard, where she helped drive drug discovery projects in cancer, cardiovascular disease, and kidney disease, among others. She also worked at the Dana-Farber Cancer Institute, where she led mid- and late-stage development of the Multiexperiment Viewer, a powerful tool for mining large genomic datasets.
Trained as a computational biologist, Eleanor has deep expertise in transcriptional profiling as well as drug discovery and development. She earned her Ph.D. bioinformatics from Oxford University under Christopher Holmes and John Quackenbush, and also holds a master’s degree in cellular and molecular biology from the University of Wisconsin-Madison.
Chris offers Diamond Age clients a unique combination of expertise in IT and bioinformatics. Previously, he was Director of Bioinformatics and IT at Granger Genetics, which used metagenomics and other molecular approaches to inform infection management and evaluate the effectiveness of cancer treatments. He also held leadership positions in IT and systems engineering for a range of organizations including the Virginia Commonwealth University (VCU) Health System.
Chris has an M.S. in in bioinformatics and a Ph.D. in integrative life sciences from VCU, where he also completed an NSF-funded postdoc in ecological genomics.
Michael DeRan, consultant
Michael brings two perspectives to Diamond Age: the skills of a computational biologist and the expertise of a bench biochemist. His work ranges from transcriptional analysis (including both bulk and single-cell RNA-seq data) to selection of promising candidates from high-throughput small-molecule screens. Prior to joining Diamond Age, he worked on early drug discovery efforts in type 2 diabetes at the Broad Institute of MIT and Harvard, and on chemical biology approaches to understanding the roles of signaling pathways in cancer at Massachusetts General Hospital.
Michael holds a Ph.D. in biochemistry from the University of Rochester School of Medicine and Dentistry, and a B.S. from Saint Bonaventure University, also in biochemistry.
Jason Warner, consultant
Jason Warner brings the insight of a molecular biologist and the technical acumen of an engineer to Diamond Age. In a previous role at Courtagen Life Sciences — where he was one of the first hires — he built the company’s bioinformatics pipeline and operation, including a team of 10, from scratch. He has also held senior roles in both data analysis and tech dev at many leading genomics startups, including Applied Biosystems, RainDance Technologies, Veritas Genetics, and Olaris Therapeutics.
Jason holds a Ph.D. in Cellular and Molecular Physiology from the Tufts University School of Medicine, and a B.A. in Biology from Cornell University. He completed his postdoc at Harvard Medical School.
Katie D’Aco, consultant
Katie combines a passion for scientific problem-solving with years of experience handling next-generation genomic sequencing data. Before joining Diamond Age, she worked at world-leading biomedical research institutions including the Novartis Institutes for Biomedical Research (NIBR), Brigham and Women’s Hospital, and the Broad Institute of MIT and Harvard’s genome sequencing center. She also worked at Life Technologies and the genome interpretation startup Knome.
Katie holds an M.S. in computational biology from Carnegie Mellon University and a BS in both biotechnology and mathematics from Tufts University.
Pete Ulintz, consultant
Pete has both deep expertise in proteomics and a wide range of computational experience covering everything from tumor heterogeneity analyses and machine learning to the digitization of ancient texts for the HathiTrust Digital Library. Before joining Diamond Age, Pete spent a decade at the University of Michigan, finishing as the bioinformatics lead for the Merajver Lab in the Rogel Cancer Center, where he worked on high-throughput sequencing data (DNA-Seq, RNA-Seq, bulk and single-cell) on aggressive breast cancer. Previously, he worked as head of bioinformatics for NextGen Sciences and as a research bioinformatician at Aventis Pharmaceuticals, now part of Sanofi.
Pete has a Ph.D. in bioinformatics from the University of Michigan, and a B.S. in physics from Wayne State University.
Abbe Clark, consultant
Abbe has deep expertise in single-cell transcriptomics and is passionate about integration of multiple data types to paint a fuller picture of disease. Before joining Diamond Age, she was a computational biologist at the Broad Institute, where she used single-cell and single-nucleus RNA sequencing data to investigate underlying mechanisms of kidney disease. She has also worked on cancer, diabetes, and Alzheimer’s disease, and has a wide range of both computational and bench skills.
Abbe has a Ph.D. in biological and biomedical sciences from Harvard University, as well as a B.S. in biochemistry and cell and molecular biology from the University of Scranton, where she graduated summa cum laude.
Bob Lonigro, consultant
Bob brings a unique combination of biostatistical training and bioinformatics experience to Diamond Age engagements. Before joining Diamond Age, he led bioinformatics development for the MI-ONCOSEQ clinical sequencing program in Arul Chinnaiyan’s lab at the University of Michigan, where he developed and deployed CLIA-certified bioinformatics pipelines to support the analysis of integrated next-generation DNA and RNA sequencing data. He also has wide-ranging biostatistical experience, having provided statistical support for a variety of cancer genomics projects including large-scale exome sequencing studies and tumor biomarker studies.
Bob has M.S. degrees in Biostatistics and Mathematics from the University of Michigan, and a B.A. in Mathematics from Rice University.
Mia Bosinger, consultant
Mia has deep expertise in analyzing large genomic datasets, including RNA-sequencing, copy number variation, whole genome or whole-exome sequencing, and single nucleotide polymorphism data. Before joining Diamond Age, Mia was a biomolecular engineer at National Cancer Institute’s The Cancer Genome Atlas Program. She played a significant role in writing the TCGA’s landmark paper “Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas,” published in The New England Journal of Medicine.
Mia holds a Ph.D. in Biomolecular Engineering and Bioinformatics from the University of California Santa Cruz, and a B.S. in Computer Science with a concentration in Bioinformatics from the University of Delaware.
Aisha AlJanahi , consultant
Aisha is well-versed in CRISPR/cas-9 off-target prediction. She came to Diamond Age fresh from a post-doctoral research position in the Boritz Lab at the National Institute of Allergy and Infectious Diseases, where she focused on characterizing HIV integration sites using ATACseq, RNAseq, and CHIPseq. Her other previous experience includes research fellowships in hematology research and retrovirology at the National Institute of Heart Lung & Blood (NHLBI) and the FDA, respectively.
Aisha has a PhD in Biochemistry and Molecular Biology from the National Institutes of Health/Georgetown University Partnership Program as well as an MS in Bioinformatics from Georgetown University.