Team

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Eleanor Howe, founder and CEO

Eleanor has been working at the cutting edge of bioinformatics for over 15 years. As founder of Diamond Age, she led the company’s evolution from a small, project-based service provider to a full-fledged consultancy that works closely with clients to tackle their most difficult research challenges.

Before founding Diamond Age, Eleanor served as the sole bioinformatician in the Center for the Development of Therapeutics at the Broad Institute of MIT and Harvard, where she helped drive drug discovery projects in cancer, cardiovascular disease, and kidney disease, among others. She also worked at the Dana-Farber Cancer Institute, where she led mid- and late-stage development of the Multiexperiment Viewer, a powerful tool for mining large genomic datasets.

Trained as a computational biologist, Eleanor has deep expertise in transcriptional profiling as well as drug discovery and development. She earned her Ph.D. bioinformatics from Oxford University under Christopher Holmes and John Quackenbush, and also holds a master’s degree in cellular and molecular biology from the University of Wisconsin-Madison. 

Eleanor is on the board of directors for WEST and speaks frequently at conferences. You can read her published scientific work here.

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Chris Friedline, consultant 

Chris offers Diamond Age clients a unique combination of expertise in IT and bioinformatics. Previously, he was Director of Bioinformatics and IT at Granger Genetics, which used metagenomics and other molecular approaches to inform infection management and evaluate the effectiveness of cancer treatments. He also held leadership positions in IT and systems engineering for a range of organizations including the Virginia Commonwealth University (VCU) Health System. 

Chris has an M.S. in in bioinformatics and a Ph.D. in integrative life sciences from VCU, where he also completed an NSF-funded postdoc in ecological genomics.

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Michael DeRan, consultant

Michael brings two perspectives to Diamond Age: the skills of a computational biologist and the expertise of a bench biochemist. His work ranges from transcriptional analysis (including both bulk and single-cell RNA-seq data) to selection of promising candidates from high-throughput small-molecule screens. Prior to joining Diamond Age, he worked on early drug discovery efforts in type 2 diabetes at the Broad Institute of MIT and Harvard, and on chemical biology approaches to understanding the roles of signaling pathways in cancer at Massachusetts General Hospital.

Michael holds a Ph.D. in biochemistry from the University of Rochester School of Medicine and Dentistry, and a B.S. from Saint Bonaventure University, also in biochemistry.

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Jason Warner, consultant

Jason Warner brings the insight of a molecular biologist and the technical acumen of an engineer to Diamond Age. In a previous role at Courtagen Life Sciences — where he was one of the first hires — he built the company’s bioinformatics pipeline and operation, including a team of 10, from scratch. He has also held senior roles in both data analysis and tech dev at many leading genomics startups, including Applied Biosystems, RainDance Technologies, Veritas Genetics, and Olaris Therapeutics.

Jason holds a Ph.D. in Cellular and Molecular Physiology from the Tufts University School of Medicine, and a B.A. in Biology from Cornell University. He completed his postdoc at Harvard Medical School. 

Katie D’Aco, consultant0

Katie combines a passion for scientific problem-solving with years of experience handling next-generation genomic sequencing data. Before joining Diamond Age, she worked at world-leading biomedical research institutions including the Novartis Institutes for Biomedical Research (NIBR), Brigham and Women’s Hospital, and the Broad Institute of MIT and Harvard’s genome sequencing center. She also worked at Life Technologies and the genome interpretation startup Knome. 

Katie holds an M.S. in computational biology from Carnegie Mellon University and a BS in both biotechnology and mathematics from Tufts University.

Pete Ulintz, consultantunnamed 6.25.37 PM

Pete has both deep expertise in proteomics and a wide range of computational experience covering everything from tumor heterogeneity analyses and machine learning to the digitization of ancient texts for the HathiTrust Digital Library. Before joining Diamond Age, Pete spent a decade at the University of Michigan, finishing as the bioinformatics lead for the Merajver Lab in the Rogel Cancer Center, where he worked on high-throughput sequencing data (DNA-Seq, RNA-Seq, bulk and single-cell) on aggressive breast cancer. Previously, he worked as head of bioinformatics for NextGen Sciences and as a research bioinformatician at Aventis Pharmaceuticals, now part of Sanofi.

Pete has a Ph.D. in bioinformatics from the University of Michigan, and a B.S. in physics from Wayne State University.

Netsanet Gebremedhin, consultant
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Net is a “T-shaped” scientist, with both wide experience and deep expertise in building complex computational pipelines for large genomic datasets. Most recently, he worked for Agenus Inc. on the development of individualized cancer vaccines, overseeing identification of neoantigens and analysis of whole exome and bulk RNA sequencing data. He has held computational roles in CLIA-accredited diagnostics labs at Partners HealthCare Personalized Medicine and Courtagen Life Sciences. His sequencing analysis experience was instrumental at New England BioLabs, where he helped develop solutions for optimizing sample preparation workflows. He was also a bench scientist at Progenika Biopharma and Wyeth Research, where he worked on a wide range of tasks such as Sanger Sequencing-based assay development for blood group genotyping, oligo synthesis, and primer design.

Net has an M.S. in Bioinformatics from Brandeis University and a B.S. in Biology and Chemistry from Addis Ababa University.